DAVID B. PARFITT, Ph.D.

Director, Teaching and Learning Center

State University of New York/Geneseo

1 College Circle; Milne 214

Geneseo, New York 14454

E-mail: parfittd@geneseo.edu

Office: (585) 245-5336           Fax: (585) 245-5769


PROFESSIONAL EXPERIENCE

State University of New York/Geneseo, Geneseo, New York

Director, Teaching and Learning Center, 2008 - present

Adjunct Lecturer, Department of Psychology, 2008-present

 

University of Rochester Medical Center, Rochester, New York

Adjunct Professor of Psychiatry, 2008- present

Assistant Professor of Psychiatry, 2005-2008

Department of Psychiatry and Rochester Center for Mind-Body Research

Middlebury College, Middlebury, Vermont

            Assistant Professor of Biology, 1999-2004

            Department of Biology and Neuroscience Program

           

EDUCATION

            Michigan State University, East Lansing, Michigan

            Postdoctoral Research Associate, 1997-1999

            Department of Psychology and Neuroscience Program

            Co-Advisors: Dr. Cheryl L. Sisk and Dr. Laura Smale

           

            University of Michigan, Ann Arbor, Michigan

            Ph.D., Neuroscience, 1997

Thesis: A multiple mating behavioral paradigm reveals discrete amygdala circuitry regulating sexual satiety in the male Syrian hamster brain.

            Committee: Dr. Sarah W. Newman (co-chair); Dr. Theresa M. Lee (co-chair);

                        Dr. Huda Akil; Dr. Richard Altschuler; Dr. Bobbi Low

            M.S., Neuroscience, 1994

            University of Pittsburgh, Pittsburgh, Pennsylvania

            B.S., cum laude, Behavioral Neuroscience, 1991

            Thesis: Restoration of pulsatile LH secretion after fasting in rhesus monkeys.

            Advisor: Dr. Judy L. Cameron

FELLOWSHIPS AND AWARDS

Middlebury College

Vermont Campus Compact, Finalist for the “Engaged Scholar” Award, 2004

 

            University of Michigan          

Duncan McCarthy Award for Excellence in Graduate Research,

                        Michigan Chapter of the Society for Neuroscience, 1996

NIH Research Fellowship, Hearing and Chemical Senses Prog., 1995-1997

NIH Research Fellowship, Reproductive Sciences Program, 1993-1995

NIMH Research Fellowship, Neuroscience Program, 1992-1993

 

            University of Pittsburgh

James Bradler Award for Excellence in Undergraduate Research,

                        Department of Behavioral Neuroscience, 1991

Senior Departmental Honors, 1991

      Tri-Beta National Biological Honor Society, 1989-1991

 

TEACHING EXPERIENCE

State University of New York/Geneseo

            PSYC251, Behavioral Research Methods, Spring 08

          

University of Rochester Medical Center

            Lecturer, Neuroscience Graduate Course, Spring 07

                        (Course Directors, M.J. Gdowski and L.M. Romanski)

            Lecturer, Psychiatry Resident Training Program, Spring 06

                        (Course Director, J.L. Fudge)

Lecturer, Neurotoxicology Graduate Course, Spring 06

            (Course Director, L.A. Opanashuk)

Lecturer, Mind Brain and Behavior, Second Year Medical School course, Fall 06, 05;                                 (Course Directors, R.F. Jozefowicz and J.L. Lyness)

Middlebury College

            BI470 Neural Disorders: Individuals, Families and Society

(service-learning senior seminar), Fall 02, 01

            BI370 Animal Physiology (with laboratory and college writing), Spring 03, 02

BI350 Endocrinology (with laboratory), Fall 02, 01, 00, 99

BI270 Early Experience and Brain Development, Winter 03

(2 week service-learning component in Romania),

            BI202 Vertebrate Life (with laboratory), Spring 01, 00

            BI150 Biology of Neurological Disorders, Fall 99

BI078 Impact of Multiple Sclerosis (service-learning), Winter 01

            FS006 Neural Disorders (service-learning first year seminar – college writing), Fall 00

            Oakland University, Rochester, Michigan

            Lecturer

            Neuroanatomy, Department of Biological Sciences, Fall 1996

            University of Michigan

            Teaching Assistant

            Dental Neuroscience, Dental School, Spring 1995, 1996

            Neuroanatomy, Department of Anatomy and Cell Biology, Winter 1995

            Introduction to Psychology as a Natural Science, Department of Psychology,                                  Winter 1994

RESEARCH SUPPORT

Current Support

2006-2008       NIMH (R03 MH075733) “Neonatal Rearing and Adult Stress Reactivity in                            C57BL/6 Mice”.

           

Completed Projects

2005-2006       Department of Psychiatry, Leonard F. Salzman Research Award, “Neonatal                          Rearing and Adult Stress Reactivity in C57BL/6 Mice”.

2003-2004       Vermont Genetics Network (NIH 1 P20 RR16462), “Rearing and Genetic                              Interactions on Mouse Social Behavior”

2002-2004       John D. and Catherine T. MacArthur Foundation and James S. McDonnell                            Research Network on Early Experience and Brain Development, “Interaction of                                   Early Rearing Environment and Genetic Background on the Development of                                Social Behaviors in C57BL/6 Mice” 

2002-2003       Vermont Genetics Network (NIH 1 P20 RR16462), “Effect of Stress and Coping                  on Reproduction”

2001-2002              NSF-ROA (M. Tetel, PI) “Effect of Controllable Stress on the Expression of              Steroid Receptor Co-Factors in the Male Syrian Hamster Brain”

2000-2001       VT-EPSCoR, “Impact of Controllable Stress on Male Hamster Reproductive                          Behavior” with Dr. Dana L. Helmreich co-PI.

SCIENTIFIC MANUSCRIPTS

* Denotes Middlebury College Undergraduate Collaborators

Parfitt, D. B., Walton, J. R., *Corriveau, E. A., & Helmreich, D. L. (2007) Early life stress effects on adult stress-induced corticosterone secretion and anxiety-like behavior in the C57BL/6 mouse are not as robust as initially thought.  Hormones and Behavior 52, 417-426.

Novak, C. M., Parfitt, D. B, Sisk, C. L., & Smale, L. (2007).  Associations between behavior, hormones, and Fos responses to novelty differ in pre- and post-pubertal grass rats.  Physiology and Behavior 90, 125-132.

Helmreich, D. L., *Crouch, M, *Dorr, N. P., & Parfitt, D. B. (2006). Peripheral triiodothyronine (T3) levels during escapable and inescapable footshock.  Physiology and Behavior 87, 114-119.


Helmreich, D. L., Parfitt, D. B., Lu, X-Y., Akil, H., & Watson, S. J. (2005).  Relation between the hypothalamic-pituitary-thyroid (HPT) axis and the hypothalamic-pituitary-adrenal (HPA) axis during repeated stress.  Neuroendocrinology 81, 183-192.

Parfitt, D. B., *Levin, J. K., *Saltstein, K. P., *Klayman, A. S., *Greer, L. M., & Helmreich, D. L. (2004).  Differential Early Rearing Environments can Accentuate or Attenuate the Responses to Stress in Male C57BL/6 Mice.  Brain Research 1016, 111-118.

*Cordner, A. P., *Herwood, M. B., Helmreich, D. L., & Parfitt, D. B. (2004).  Antidepressants block the effects of inescapable stress on male reproductive behavior and corticotropin releasing hormone mRNA expression in the hypothalamic paraventricular nucleus of the Syrian hamster (Mesocricetus auratus)Journal of Neuroendocrinology 16, 628-636.

Richardson, H. N., Nelson, A. L. A., Ahmed, E. I., Parfitt, D. B., Romeo, R. D., & Sisk, C. L. (2004).  Female pheromones stimulate release of luteinizing hormone and testosterone without altering GnRH mRNA in adult male Syrian hamsters (Mesocricetus auratus)General and Comparative Endocrinology 138, 211-217.

*Holmer, H. K., *Rodman, J. E., Helmreich, D. L., & Parfitt, D. B. (2003).  Differential effects of chronic escapable versus inescapable stress on male Syrian hamster (Mesocricetus auratus) reproductive behavior.  Hormones and Behavior 43, 381-387.

*Boscarino, B. T. & Parfitt, D. B. (2002).  Chronic oral administration of clomipramine decreases sexual behavior in the male Syrian hamster (Mesocricetus auratus)Physiology and Behavior 75, 361-366.

Richardson, H. N., Parfitt, D. B., Thompson, R. C., & Sisk, C. L. (2002).  Redefining gonadotropin-releasing hormone (GnRH) cell groups in the male Syrian hamster: testosterone regulates GnRH mRNA in the tenia tecta.  Journal of Neuroendocrinology, 14, 375-383.

Williams, N. I., Helmreich, D. L., Parfitt, D. B., Caston-Balderrama, A., & Cameron J. L. (2001).  Evidence for a causal role of low energy availability in the induction of menstrual cycle disturbances during strenuous exercise training.  Journal of Clinical Endocrinology and Metabolism, 86, 5184-5193.

Williams, N. I., Caston-Balderrama, A. L., Helmreich, D. L., Parfitt, D. B., Nosbisch, C., & Cameron, J. L. (2001).  Induction of menstrual cycle disturbances in cynomolgus monkeys during strenous exercise training: longitudinal changes in reproductive hormones and menstrual cyclicity.  Endocrinology, 142, 2381-2389.

Parfitt, D. B., Thompson, R. C., Richardson, H. N., Romeo, R. D., & Sisk, C. L. (1999).  Pubertal increases in GnRH mRNA expression in specific neuronal subpopulations of the male Syrian hamster brain.  Journal of Neuroendocrinology, 11, 621-627.

Romeo, R. D., Parfitt, D. B., Richardson, H. N., & Sisk, C. L. (1998).  Pheromones elicit equivalent levels of Fos-immunoreactivity in prepubertal and adult male Syrian hamsters.  Hormones and Behavior, 34, 48-55.

Parfitt, D. B. & Newman, S. W. (1998).  Fos-immunoreactivity within the extended amygdala is correlated with the onset of sexual satiety.  Hormones and Behavior, 34, 17-29.

Newman, S. W., Parfitt, D. B., & Kollack-Walker, S. W. (1997).  Mating induced c-fos expression patterns complement and supplement observations after lesions in the male Syrian hamster brain.  New York Academy of Sciences, 807, 239-259.

Goodman, R. L., Parfitt, D. B., Evans, N. P., Dahl, G. E., & Karsch, F. J. (1995).  Endogenous opioid peptides control the amplitude and shape of gonadotropin-releasing hormone pulses in the ewe.  Endocrinology, 136, 2412-2420.

Schreihofer, D. A., Parfitt, D. B., & Cameron, J. L. (1993).  Suppression of luteinizing hormone secretion after short-term fasting in male rhesus monkeys: the role of metabolic versus stress signals.  Endocrinology, 132, 1881-1889.

Parfitt, D. B., Church, K. R., & Cameron, J. L. (1991).  Restoration of pulsatile LH secretion after fasting in male rhesus monkeys (Macaca mulatta): dependence on size of refeed meal.  Endocrinology, 129, 749-756.

ABSTRACTS PRESENTED AT NATIONAL MEETINGS

* Denotes Middlebury College Undergraduate Collaborators

Parfitt, D. B. (2007).  Developing an early life stress model that reliably alters adult neuroendocrine and behavioral stress-reactivity in C57BL/6 mice: neonatal handling vs. maternal separation.  International Behavioral Neuroscience Society.

Parfitt, D. B., Helmreich, D. L., & Walton, J. R. (2006).  Time of day influences the adult behavioral stress response in differentially reared male C57BL/6 mice subjected to an emotionality test battery.  Society for Neuroscience. Abstract 59.12.

Helmreich, D. L., Parfitt, D. B., & Walton, J. R. (2006).  Dexamethasone regulation of stress-induced transcription of HPA axis secretagogues.  Society for Neuroscience.  Abstract 563.15.

Parfitt, D. B. (2005).  International service-learning as a model for developing scientific literacy, community engagement, and collaborative research opportunities.  FASEB Journal 19 (5): A1341, Part 2 Suppl. S.

Parfitt, D. B., Corriveau, E. A.*, Stamper, K. S.*, Falcone, T. E.*, Daviau, E. D.*, & Helmreich, D. L. (2004).  Does time of day of neonatal early handling or maternal separation differentially impact mRNA expression for HPA axis regulators in adult male C57BL/6 mice?  Society for Neuroscience. Abstract 545.15. 

Corriveau, E. A.*, Falcone, T. E.*, Daviau, E. D.*, Helmreich, D. L., & Parfitt D. B. (2004).  Physiological effects of maternal separation are modulated by time of day and maternal behavior in C57BL/6 mice.  Society for Behavioral Neuroendocrinology.  Abstract 17.

Dorr, N. P.*, Tory, H. O.*, Parfitt, D. B., & Helmreich D. L. (2004).  Does stressor controllability alter corticosterone suppression by dexamethasone?  Society for Behavioral Neuroendocrinology.  Abstract 32.

Helmreich, D. L., Parfitt, D. B., *Ene S., *Erickson-Schroth, L., Lu, X., Akil, H., & Watson S. J. (2003).  Effects of foot-shock stress on the activity of the hypothalamic-pituitary-thyroid (HPT) axis and related peptides.  Society for Neuroscience.  Abstract 396.7.

*Saltstein, K. P., Helmreich, D. L., & Parfitt D. B. (2002).  Maternal separation alters the adult response to stress in male C57BL/6 mice.  Society for Neuroscience.  Abstract 571.17.

Helmreich, D. L., *Crouch, M., & Parfitt D. B. (2002).  Does controllable or non-controllable foot-shock stress alter PVN TRH mRNA levels?  Society for Neuroscience.  Abstract 865.16.

*Cordner, A. P., Helmreich, D. L., & Parfitt D. B. (2002).  Antidepressant administration prevents the effect of uncontrollable stress on male reproductive behavior in the Syrian hamster (Mesocricetus auratus)Society for Behavioral Neuroendocrinology.  Abstract 28.

Parfitt, D. B., *Levin, J. K., *Greer, L. M., & Betourney M. A. (2001).  Effect of early rearing environment on the development of social behaviors in C57BL/6 mice.  Society for Neuroscience.  Abstract 737.6.

Helmreich, D. L., *Crouch, M., & Parfitt D. B. (2001).  Thyroid hormone levels during controllable and non-controllable stress.  Society for Neuroscience.  Abstract 732.7.

*Rodman, J. E., Helmreich, D. L., *Holmer, H. K., & Parfitt, D. B. (2001).  Two days of controllable or uncontrollable stress does not inhibit mating in the male Syrian hamster (Mesocricetus auratus)Society for Behavioral Neuroendocrinology.  Abstract 7.

Parfitt, D. B., Novak, C. M., Sisk, C. L., & Smale L. (2000).  Differential neuroendocrine and Fos response to a novel environment in juvenile and adult Arvicanthis niloticusSociety for Neuroscience, Abstract 471.10.

Richardson, H. N., Romeo, R. D., Venier, J. E., Parfitt, D. B., & Sisk, C. L. (2000).  Androgenic regulation of the hypothalamic-pituitary-gonadal axis before and after pubertal development.  Joint Meeting of the VI th International Conference on Hormones, Brain, and Behavior and the Society for Behavioral Neuroendocrinology.

Parfitt, D. B., Thompson, R. C., Richardson, H. N., Romeo, R. D., & Sisk, C. L. (1999).  Differential neuroendocrine response to female pheromones in juvenile and adult male Syrian hamsters. Society for Neuroscience, Abstract 582.16. 

Richardson, H. N., Parfitt, D. B., Thompson, R. C., & Sisk, C. L. (1999).  Testosterone (T) regulation of gonadotropin releasing hormone (GnRH) mRNA in juvenile and adult male Syrian hamsters. Society for Neuroscience, Abstract 582.17.

Parfitt, D. B., Richardson, H. N., Romeo, R. D., Wissman, A. M., & Sisk, C. L. (1998).  Quantification of gonadotropin releasing hormone (GnRH) mRNA in the male Syrian hamster during puberty.  Society for Neuroscience, Abstract 545.3.

Romeo, R. D., Parfitt, D. B., Richardson, H. N., & Sisk, C. L. (1998).  Pheromones elicit equivalent levels of Fos-immunoreactivity in prepubertal and adult male hamsters.  Society for Behavioral Neuroendocrinology, Abstract 9.

Parfitt, D. B., Coolen, L. M., Newman, S. W., & Wood, R. I. (1996).  Lesions of the posterior medial nucleus of the amygdala delay sexual satiety.  Society for Neuroscience, Abstract 67.8.

Parfitt, D. B. & Newman, S. W. (1996).  Mating induced neuronal activation within the BNST supports the concept of an extended amygdala.  Conference on Reproductive Behavior, Abstract 89.

Parfitt, D. B. & Newman, S. W. (1995).  Specific neuronal activation in the medial amygdala after mating is correlated with the onset of sexual satiety.  Society for Neuroscience, Abstract 282.5.

Parfitt, D. B. & Newman, S. W. (1994).  Distribution of neuropeptide Y in the male Syrian hamster brain.  Society for Neuroscience, Abstract 656.5.

Lehman, M. N., Berriman, S. L., Jansen, H. T., Parfitt, D. B., Dahl, G. E., Evans, N. P., & Karsch, F. J. (1994).  Is Fos expression in GnRH and other neurons during the estradiol-induced LH surge of the ewe associated with neurosecretory or behavioral events?  Society for the Study of Reproduction, Abstract 521.

Parfitt, D. B., Evans, N. P., Dahl, G. E., & Karsch, F. J. (1993).  Blockade of endogenous opiates increase pulse duration, amplitude, and interpulse secretion of GnRH in the ovariectomized ewe.  Society for Neuroscience, Abstract 571.10.

Schreihofer, D. A., Parfitt, D. B., & Cameron, J. L. (1991).  Effects of overfeeding on subsequent fasting-induced suppression of pulsatile LH secretion in male rhesus monkeys (Macaca mulatta).  Society for Neuroscience, Abstract 544.8.

Helmreich, D. L., Parfitt, D. B., & Cameron, J. L. (1991).  Definition of metabolic states associated with the suppression and restoration of LH secretion caused by fasting and refeeding in rhesus monkeys.  Society for Neuroscience, Abstract 544.7.

Parfitt, D. B., Church, K. R., & Cameron, J. L. (1990).  Fasting-induced suppression of pulsatile LH secretion is rapidly reversed by refeeding in rhesus monkeys (Macaca mulatta).  Society for Neuroscience, Abstract 168.18.

Schreihofer, D. A., Parfitt, D. B., & Cameron, J. L. (1990).  Evidence that the suppression of hypothalamic-pituitary-gonadal axis activity during fasting results from a nutritional signal and not the psychological stress of food deprivation.  Society for Neuroscience, Abstract 168.17.

Cameron, J. L., Nosbisch, C., Helmreich, D. L., & Parfitt, D. B. (1990).  Reversal of exercise induced amenorrhea in female cynomolgus monkeys (Macaca fascicularis) by increasing food intake.  Endocrine Society, Abstract 1042.

Cameron, J. L., Helmreich, D. L., Parfitt, D. B., & Nosbisch, C. (1990).  Slowing of pulsatile LH and testosterone secretion after a one-day fast in adult male rhesus monkeys.  Serono Symposium on the Neuroendocrine Regulation of Reproduction.  Abstract 462.

STUDENT PRESENTATIONS AT REGIONAL MEETINGS

* Denotes Middlebury College Undergraduate Collaborators

*Corriveau, E. A., *Falcone, T. E., *Daviau, E. D., Helmreich, D. L., & Parfitt, D. B. (2004).  Physiological Effects of Maternal Separation are Influenced by Light Cycle and Maternal Behavior in C57BL/6 Mice.  8th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #23.  Norton, MA.

*Dorr, N. P., Helmreich, D. L., & Parfitt, D. B. (2004).  Footshock-induced Transcription of CRH and AVP in the Adult Rat Hypothalamus.  8th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #24.  Norton, MA.

*Selgrade, R. A., Parfitt, D. B., & Helmreich, D. L. (2004).  The Behavioral Effects of Hypothyroidism in Adult Rats.  8th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #58.  Norton, MA.

*Herwood, M. B., Helmreich, D. L., & Parfitt, D. B. (2003).  The Effects of Chronic Escapable Versus Inescapable Stress and Antidepressants on CRH mRNA Expression in the Male Syrian Hamster (Mesocricetus auratus).  7th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #23.  Norton, MA.

*Klayman, A. S., *Nagel, A. L., Parfitt, D. B., & Helmreich, D. L. (2003).  CRH and GR mRNA Expression in Differentially Reared C57BL/6 Mice.  7th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #21.  Norton, MA.

*Cassidy L., Parfitt, D. B., & Helmreich D. L. (2002).  Corticosterone and Behavioral Measurements in Two Animal Models of Depression: The Effects of Antidepressants or dexamethasone.  6th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #14.  Wellesley, MA.

*Cordner A. P., Helmreich D. L., & Parfitt D. B. (2002).  Antidepressant Administration Prevents the Adverse Effect of Stress on Male Reproductive Behavior in the Syrian Hamster (Mesocricetus auratus).  6th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #15.  Wellesley, MA.

*Crouch M., Parfitt D. B., & Helmreich D. L. (2002).  Stressor controllability influences the behavior of the adult male rat in the Open Field test, the Neophobia test and the Forced Swim test.  6th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #13.  Wellesley, MA.

*Levin J. K. , *Saltstein K. P., Major V., & Parfitt D. B. (2002).  The Effect of Early Rearing Environment on the Behavioral Response to Tests of Fear and Anxiety in the Male C57BL/6 Mouse.  6th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON).  Abstract #8.  Wellesley, MA.

*Bender, K. & Parfitt, D. B. (2001).  Does the visible burrow system create a semi-natural stress environment for the Syrian hamster?  5th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON). Abstract #12.  Wellesley, MA.

*Boscarino, B. T. & Parfitt, D. B. (2001).  The effect of clomipramine on sexual behavior in the male Syrian hamster.  5th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON). Abstract #3. Wellesley, MA.

*Crouch, M., Parfitt, D. B., & Helmreich, D. L. (2001).  Thyroid hormone (T3) levels in the adult male rat following acute stress.  5th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON). Abstract #11.  Wellesley, MA.

*Greer, L. M. & Parfitt, D. B. (2001).  The effect of maternal deprivation on C57BL/6 mouse behavior in a novel environment.  5th Annual Conference of the North East Under/graduate Research Organization for Neuroscience (NEURON). Abstract #16. Wellesley, MA.